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    Development of soluble glasses for biomedical use Part I: in vitro solubility measurement.

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    In this study soluble glasses have been developed for biomedical applications containing P2O5 as a network former and CaO and Na2O as modifiers. This study shows that as expected, the glasses have an inverse exponential relationship between solubility and CaO content. Furthermore, there is evidence for compositional related non-linearity in the dissolution of the glasses with time. This is thought to be due to either layer formation on the glass surface hindering ion diffusion, ion exchange process or change of ionic strength of the solution. Bioactivity of these glasses is indicated by the formation of a brushite precipitate, a precursor to apatite formation. Further evidence for bioactivity is also presented in the second part of this paper.

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    Description

    Title : Development of soluble glasses for biomedical use Part I: in vitro solubility measurement.
    Author(s) : K Franks, I Abrahams, JC Knowles
    Abstract : In this study soluble glasses have been developed for biomedical applications containing P2O5 as a network former and CaO and Na2O as modifiers. This study shows that as expected, the glasses have an inverse exponential relationship between solubility and CaO content. Furthermore, there is evidence for compositional related non-linearity in the dissolution of the glasses with time. This is thought to be due to either layer formation on the glass surface hindering ion diffusion, ion exchange process or change of ionic strength of the solution. Bioactivity of these glasses is indicated by the formation of a brushite precipitate, a precursor to apatite formation. Further evidence for bioactivity is also presented in the second part of this paper.
    Keywords : biomat, glasses, vitro, october, other

    Subject : unspecified
    Area : Other
    Language : English
    Year : 2000

    Affiliations UCL
    Journal : Journal of Materials Science: Materials in Medicine
    Volume : 11
    Issue : 10
    Publisher : KLUWER ACADEMIC PUBL
    Pages : 609-614
    Url : http://discovery.ucl.ac.uk/110546/

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    Jonathan's Peer Evaluation activity

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