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    block this user Mahendra Kumar Trivedi

    Independent researcher

    Las Vegas Naveda
    Trivedi Global Inc.
    Trivedi Science Research Laboratory Pvt. Ltd

    Spectroscopic Characterization of Chloramphenicol and Tetracycline: An Impact of Biofield Treatment

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    Objective: Chloramphenicol and tetracycline are broad-spectrum antibiotics and widely used against varietyof microbial infections. Nowadays, several microbes have acquired resistance to chloramphenicol and tetracycline.The present study was aimed to evaluate the impact of biofield treatment for spectroscopic characterization ofchloramphenicol and tetracycline using FT-IR and UV-Vis spectroscopy. Methods: The study was performed in two groups (control and treatment) of each antibiotic. The control groupsremained as untreated, and biofield treatment was given to treatment groups. Results: FT-IR spectrum of treated chloramphenicol exhibited the decrease in wavenumber of NO2 from 1521cm-1 to 1512 cm-1 and increase in wavenumber of C=O from 1681 cm-1 to 1694 cm-1 in acylamino group. It may bedue to increase of conjugation effect in NO2 group, and increased force constant of C=O bond. As a result, stability ofboth NO2 and C=O groups might be increased in treated sample as compared to control. FT-IR spectrum of treatedtetracycline showed the downstream shifting of aromatic C-H stretching from 3085-3024 cm-1 to 3064-3003 cm-1 andC=C stretching from 1648-1582 cm-1 to 1622-1569 cm-1 and up shifting of C-N stretching from 965 cm-1 to 995 cm-1.It may be due to enhanced conjugation effect in tetracycline, and increased force constant of C-N (CH3) bond oftetracycline as compared to control. The results indicated the enhanced stability of treated tetracycline as comparedto control. UV-Vis spectra of biofield treated chloramphenicol and tetracycline showed the similar lambda max (λmax)to their respective control. It revealed that the chromophore groups of both antibiotics remained same as controlafter the biofield treatment. Conclusion: Based on FT-IR spectroscopic data, it is speculated that due to increase in bond strength andconjugation effect after biofield treatment, the chemical stability of both the drugs might be increased as comparedto control.

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    Title : Spectroscopic Characterization of Chloramphenicol and Tetracycline: An Impact of Biofield Treatment
    Author(s) : Mahendra Kumar Trivedi
    Abstract : Objective: Chloramphenicol and tetracycline are broad-spectrum antibiotics and widely used against varietyof microbial infections. Nowadays, several microbes have acquired resistance to chloramphenicol and tetracycline.The present study was aimed to evaluate the impact of biofield treatment for spectroscopic characterization ofchloramphenicol and tetracycline using FT-IR and UV-Vis spectroscopy. Methods: The study was performed in two groups (control and treatment) of each antibiotic. The control groupsremained as untreated, and biofield treatment was given to treatment groups. Results: FT-IR spectrum of treated chloramphenicol exhibited the decrease in wavenumber of NO2 from 1521cm-1 to 1512 cm-1 and increase in wavenumber of C=O from 1681 cm-1 to 1694 cm-1 in acylamino group. It may bedue to increase of conjugation effect in NO2 group, and increased force constant of C=O bond. As a result, stability ofboth NO2 and C=O groups might be increased in treated sample as compared to control. FT-IR spectrum of treatedtetracycline showed the downstream shifting of aromatic C-H stretching from 3085-3024 cm-1 to 3064-3003 cm-1 andC=C stretching from 1648-1582 cm-1 to 1622-1569 cm-1 and up shifting of C-N stretching from 965 cm-1 to 995 cm-1.It may be due to enhanced conjugation effect in tetracycline, and increased force constant of C-N (CH3) bond oftetracycline as compared to control. The results indicated the enhanced stability of treated tetracycline as comparedto control. UV-Vis spectra of biofield treated chloramphenicol and tetracycline showed the similar lambda max (λmax)to their respective control. It revealed that the chromophore groups of both antibiotics remained same as controlafter the biofield treatment. Conclusion: Based on FT-IR spectroscopic data, it is speculated that due to increase in bond strength andconjugation effect after biofield treatment, the chemical stability of both the drugs might be increased as comparedto control.
    Keywords : biofield,trivedi effect,the trivedi effect,mahendra trivedi, mahendra kumar trivedi

    Subject : Pharmaceutica Analytica Acta
    Area : Open Access
    Language : English
    Year : 2015

    Affiliations Trivedi Global Inc.
    Trivedi Science Research Laboratory Pvt. Ltd
    Journal : Pharmaceutica Analytica Acta
    Volume : 6
    Issue : 7
    Publisher : open access
    Doi : 10.4172/21532435.1000395

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    Mahendra's Peer Evaluation activity

    Downloads 35331
    Views 200
    Following... 21
    • Alejandro Engelmann, Independent researcher, Library, Swedish University of Agricultural Sciences, Uppsala, Sweden.
    • Selma Dorrestein, Student, Master Level, University of Amsterdam.
    • Francisco Herrera, Publisher, UNIVERSITY OF GRANADA.
    • Ralf Steinmetz, Professor, university.
    • Gregory Dudek, Professor, McGill University, School of Computer Science, Montreal, Canada.
    • Umberto Straccia, Senior Research Fellow, ISTI - CNR.
    • Sorin Cotofana, Associate Professor, Deft University of Technology, Faculty of Electrical Engineeting, Mathematics, and Computer Science. Computer Engineering, Delft, The Netherlands.
    • Stefan Trausan-Matu, Professor, Computer Science Department, Politehnica University of Bucharest, Research Institute for Artificial Intelligence.
    • Jean Quisquater, Professor, UCL Crypto Group.
    • Markus Jakobsson, Principal Research Fellow, PayPal, FatSkunk, Indiana University.
    • Michael Elad, Professor, Technion - Israel institute of Technology.
    • Andrew Lumsdaine, Professor, Indiana University.
    • Mikael Nilsson, Student, Ph.D. Level, Royal Institute of Technology, Stockholm, Sweden.
    • Emilie Combet, Lecturer, MVLS, University of Glasgow, Glasgow, Centre for Population and Health Sciences, Life-course Nutrition and Health.
    • Werner Muller, Professor, Faculty of Life Science, University of Manchester, Manchester.
    • Syam Mohan, Senior Research Fellow, Pharmacology, University of Malaya, Malaysia.
    • Ramy K Aziz, Lecturer, Department of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
    • Paweł K. Jędrzejko, Associate Professor, Department of American and Canadian Studies of the Institute of English Cultures and Literatures, University of Silesia in Katowice, Poland.
    • Nader Ale Ebrahim, Independent researcher, Research Support Unit, Centre of Research Services, Institute of Research Management and Monitoring (IPPP), University of Malaya, Malaysia.
    • Kelli Barr, Student, Ph.D. Level, Department of Philosophy and Religion Studies, University of North Texas, Denton, TX.
    • Pandelis Perakakis, Post Doctorate, Economics department, Universitet Jaume I, Castellon.

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